ANTIGENICITY OF THE M PROTEINS OF GROUP A HEMOLYTIC STREPTOCOCCI
نویسندگان
چکیده
منابع مشابه
Antigenicity of the M Proteins of Group a Hemolytic Streptococci
Highly purified M proteins were used for determining cutaneous hypersensitivity and type-specific circulating antibodies in normal adults and infants. 80% of 91 adults and 8% of 59 infants exhibited a transient delayed cutaneous reaction to at least two of types 12, 14, and 24 M proteins. Antibodies assayed by passive hemagglutination were observed in 90% of the adults and 13% of the infants. V...
متن کاملTyping Group a Hemolytic Streptococci
Two methods of typing group A hemolytic streptococci have been described: slide agglutination and anti-M precipitin tests. The first, developed by Griffith (1), is more extensively used. I t has the distinct advantages of requiring small amounts of serum and culture, and of a quick reaction time when all conditions are favorable. I t has certain disadvantages: The granular growth of some strain...
متن کاملsurvey of carrier rate of group a hemolytic streptococci
this study was undertaken in order to ascertain the carrier rate of group a hemolytic streptococci in the throats of pupils in selected schools of tehran, and to evaluate the role of socio-economical factors on carrier state. during the period of six months, 7020 children and adolescents, aged 10 to 17, were studied. these pupils were visited at their schools and their socio-economical level wa...
متن کاملStudies on the biosynthesis of the M-protein of group A hemolytic streptococci.
A preliminary report of the biosynthesis of the M-protein by nonproliferating group A hemolytic streptococci was presented by Fox and Krampitz (1954). The M-protein is the somatic antigen which confers type specificity upon group A streptococci (Lancefield, 1940). The experiments presented now represent an attempt to define some of the conditions which are required for synthesis of M-protein. T...
متن کاملThe Endotoxic Properties of Lysates of Group a Hemolytic Streptococci
Suspensions of group A streptococci were subjected to mechanical disruption by shaking with glass beads. The supernatant solutions produced severe delayed inflammatory reactions on intradermal injection into normal rabbits. Intravenous injections caused systemic reactions characterized by fever, leucopenia, and peripheral vasomotor phenomena. These effects were more pronounced in rabbits which ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1966
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.124.6.1135